Proton Magnetic Resonance Spectroscopy of Normal Breast Tissues in Women Volunteers

• Conditions: Breast Neoplasms

• Registration Number: NCT00155090
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

Magnetic resonance spectroscopy (MRS) is a diagnostic technique in MRI that distinguishes various metabolites on the basis of their slightly different chemical shifts or resonance frequencies. The Proton is the most abundant nucleus in the body. We will try to establish the typical proton MRS pattern of normal women breasts to be a guideline for future further investigations.

Detailed Description

There are few reports regarding proton MRS in normal female breasts. The fibroglandular tissues and fat are the two major gross components in the breast. The water content in the fibroglandular tissues is much higher than that in the fat. There is still no documented report discussing proton MRS in normal female breasts of premenopausal and postmenopausal women. Our study is to evaluate the proton MRS findings among normal premenopausal and postmenopausal women breasts, to find out if there are statistical differences on the main proton MRS patterns, water and lipid peak intensities and ratios between the two groups.

Study Timeline

• Status Verified: 2005-01
• Study Start: 2005-01
• Study First Submitted: 2005-09-09
• Study First Submitted QC: 2005-09-09
• Last Update Submitted: 2005-09-09
• Study First Posted: 2005-09-12
• Last Update Posted: 2005-09-12
• Study Completion: 2005-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

• women age ranged 30 years of age or older, with normal mammograms or ultrasound in recent 3 months

Exclusion Criteria

• any women not fulfilling the inclusion criteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

National Taiwan University Hospital; 🇨🇳 Taipei, Taiwan