Clinical and Radiographic Assessment of Nano-Bioactive Glass Combined With I-PRF Scaffold in Vital Pulp Treatments in Mandibular Molars With Closed Apices: A Triple Blinded "Randomized Controlled Trial"
试验速览
- 阶段
- 不适用
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Clinical , Radiographic and Success rate
研究概览
简要总结
Clinical, Radiographic and pain assessment of Vital pulp treatment in patients suffering from irreversible pulpitis in mature permanent molars. Total pulpotomy is investigated using I-prf only vs I-prf mixed with Nano-bioactive glass.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 14 Years 至 32 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients suffering from Symptomatic irreversible pulpitis in mature mandibular molars only will be involved.
- •Tooth should give positive response to cold test
- •Haemostasias should be achieved after total pulpotomy
- •The tooth is restorable and free from advanced periodontal disease, cracks and splits.
- •Patients should be free from any systemic disease that may affect normal healing and predictable outcome.
- •Patients who will agree to the consent and will commit to follow-up period.
- •Patients with mature root apices
- •Patients with no internal or external resorption and no periapical lesions
- •Soft tissues around the tooth are normal with no swelling or sinus tract.
排除标准
- •Patients with immature roots.
- •Haemostasias after 10 minutes can not be controlled after total pulpotomy
- •Patients with any systemic disease that may affect normal healing.
- •Patients with periapical lesions or infections.
- •Pregnant females.
- •Patients who could/would not participate in a 6 months follow-up.
- •Patients with fistula or swelling
- •Patients with necrotic pulp.
- •Patients with old age.
研究组 & 干预措施
Total pulpotomy with I-PRF only
Total pulpotomy is done in mature permanent molars followed by I-prf application. Topped with BC putty for coronal seal, RMGI and restored with composite as final restoration
干预措施: Total pulpotomy with I-prf mixed with Nano-bioactive glass (Procedure)
结局指标
主要结局
Clinical , Radiographic and Success rate
时间窗: 6 month follow up
Presence or absence of clinical signs and symptoms + Radiographic periapical assessment + success rate based on Radiographic findings
次要结局
- Pain intensity(Within the first 24 hrs upto the 7th day)
研究者
Noor Mohammed Kamal Eldeen Ahmed Mohmammed Sayed
Resident of Endodontics
Cairo University