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Clinical and Radiographic Evaluation of Nano Silver Fluoride Versus Calcium Hydroxide in Indirect Pulp Treatment

Not Applicable
Completed
Conditions
Deep Caries
Interventions
Registration Number
NCT04005872
Lead Sponsor
Cairo University
Brief Summary

The management of deep carious lesions approaching a healthy pulp is considered a challenge to the dental practitioner. The conventional treatment of deep carious lesions requires the removal of all infected and affected dentin to avoid more cariogenic activity.

Detailed Description

This study is designed to assess the clinical and radiographic effectivness of nano silver fluoride versus calcium hydroxide in an indirect pulp treatment of deep carious second primary molars. This clinical study is important because World Health Organization (WHO) has reported that school children experience to dental caries was 60-90% of worldwide (P. D. Garkoti et al., 2015).

This clinical trial has potential benefits to patients where indirect pulp treatment preserves pulp vitality by partial caries removal without exposing pulp. Several materials have been used for indirect pulp technique including calcium hydroxide (Metalita M et al., 2016).

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
40
Inclusion Criteria

Patients:

  • Cooperative children.
  • Both genders.
  • In age range from 4 to 7 years.

Teeth:

  • Vital second primary molars with deep caries limited to occlusal surface.
  • No clinical signs or symptoms of irreversible pulpitis or pulp necrosis.
  • No radiographic abnormalities
  • Restorable teeth.
Exclusion Criteria
  • • Children with known history of allergy to any of the tested materials.

    • Children with systemic conditions.
    • Parents who refused to participate.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Calcium HydroxideCalcium hydroxideCalcium hydroxide placed on the last soft carious layer approaching the pulp
Nano Silver FluorideNano Silver Fluoride2 drops of nano silver fluoride (NSF) applied on the last soft carious layer using micro brush
Primary Outcome Measures
NameTimeMethod
Sinus or fistula tract12 months

Clinical examination by operator

Spontaneous pain or pain on biting12 months

By asking patient

Pain on percussion12 months

By the back of mirror

Swelling12 months

Clinical examination by operator

Mobility12 months

Clinical examination by operator

Secondary Outcome Measures
NameTimeMethod
Furcation or perapical radiolucency12 months

Periapical radiograph

External or internal root resorption12 months

Periapical radiograph

Widening periodontal membrane space12 months

Periapical radiograph

Trial Locations

Locations (1)

Heba Mohamed Refaat Fouad Genena

🇪🇬

Cairo, Egypt

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