Efficacy of BBG-01 (Bifidobacterium breve) on pre and postoperative infectious complications of infants in Juntendo University Hospital
Not Applicable
Recruiting
- Conditions
- Pediatric inpatients scheduled for gastrointestinal and urogenital surgery
- Registration Number
- JPRN-UMIN000005175
- Lead Sponsor
- Division of Laboratory for Probiotic Research, Juntendo University
- Brief Summary
BBG-01 was well tolerated without adverse effects, and postoperative infectious complications were significantly decreased. Fecal analysis showed increased Bifidobacterium and decreased Enterobacteriaceae, Clostridium difficile, and Pseudomonas. Concentrations of fecal acetic acid were significantly increased, maintaining fecal pH at <7.0. The incidence of detecting bacteria in blood was significantly reduced.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
- A subject who cannot ingest the test diet due to intestinal dysfunction. - A subject whose operation is cancelled. - A subject who is not suitable for the trial defined by the attending researcher.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Postoperative infectious complications - Sepsis - Intestinal microbiota - Gastrointestinal function
- Secondary Outcome Measures
Name Time Method - Length of hospital stay - Blood biochemical indicators - Intestinal environment