Phase I Trial of Infusional Fluorouracil, Leucovorin, Oxaliplatin, and Irinotecan(FOLFOXIRI) for Metastatic or Reccurence Colorectal Cancer
Phase 1
- Conditions
- Colorectal Cancer
- Registration Number
- JPRN-UMIN000000883
- Lead Sponsor
- Department of Clinical Oncology, Conprehensive Cancer Center, Saitama Medical University International Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
Not provided
Exclusion Criteria
1. Severe infection 2. 3. History of Irinotecan, and Oxaliplatin use 4. Severe complication 5. 6. Regular use of 7. History of thromboembolism 8. Unmanageable hyper tention 9. Active ulcer 10. Symptomatic brain metastasis 11. 12. 13. 14. History of radiotherapy 15. Massive pleural effusion required drainage 16. Persistent diarrhea 17. 18. 19. HBs antigen and HCV antigen positive 20. Pregnancy or the desire to preserve fecundity 21. 22. Psychological disease deemed to unacceptable for inclusion to the study 23. 24. Inadequate physical condition, as diagnosed by primary physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method