pilot study of intraarterial 5-fluorouracil/interferon combination therapy for advanced hepatocellular carcinoma patients who do not response to intraarterial 5-fluorouracil/cisplatin combination therapy.
Phase 2
- Conditions
- advanced hepatocellular caricinoma
- Registration Number
- JPRN-UMIN000002928
- Lead Sponsor
- Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical, Hiroshima University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
1) With other malignant disease. 2) A pregnant woman, or a woman suspected of pregnancy. 3) With severe infectious disease. 4) With history of severe allergy. 5) With severe renal function disease. 6) With severe allergy for 5FU or IFN. 7) With severe bone marrow supression. 8) With pulmonary fibrosis. 9) with shosaikoto 10) with autoimmune hepatitis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method response rate
- Secondary Outcome Measures
Name Time Method 1) overall survival 2) time to progression 3) safety