Effect of remote ischemic post-conditioning on neurologic and cardiac recovery in out-of-hospital cardiac arrest

Chonnam National University Hospital0 个研究点目标入组 118 人开始时间: 待定最近更新: 2019年3月11日

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•adult greater than 19 years old
•out-of-hospital cardiac arrest with sustained restoration of spontaenous circulation
•comatose following restoration of spontaenous circulation
•time of enrollment within 6 hours from restoration of spontaneous circulation
•undergoing targeted temperature management
•cardiac arrest from medical cause (cardiac or other medical cause)

•1) Pre-existing dementia, brain injury, or dependence on others (cerebral performance category scale??3)
•2) Traumatic etiology for cardiac arrest
•3) Protected population (pregnant, prisoner)
•4) in-hospital cardiac arrest
•5) Known bleeding diathesis
•6) suspected or confirmed acute intracranial hemorrhage
•7) suspected or confirmed acute ischemic stroke
•8) Known limitations in therapy and do-not-resuscitate order
•9) known disease making 180-day survival unlikely
•10) >6 hours from restoration of spontaneous circulation to randomization
•11) cardiac arrest from asphyxia (hanging, foreign body airway obstruction), drowning, drug overdose, or electrocution
•12) peripheral vascular disease (Deep vein thrombosis, arteriosclerosis obliterans)
•13) systolic blood pressure < 80 mmHg in spite of fluid loading/vasopressor and/or inotropic medication

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