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Clinical Trials/NCT04211311
NCT04211311
Completed
Not Applicable

"Feasibility of High-intensity Interval Training (HIIT) as Hybrid Exercise Using Functional Electrical Stimulation Leg-cycling (FEScycling) and Ski Ergometer (SkiErg) With the Arms for People With Chronic Spinal Cord Injury Paraplegia"

University of Southern Denmark1 site in 1 country8 target enrollmentJanuary 30, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Spinal Cord Injuries
Sponsor
University of Southern Denmark
Enrollment
8
Locations
1
Primary Endpoint
Number of serious adverse events
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

This study examines safety and feasibility of a study protocol using a combination of functional electrical legcycling with voluntary armwork (hybrid training) as either skiergometer or armcycling in high intensity intervals for persons with spinal cord injury paraplegia.

Detailed Description

Cardiovascular disease is one of the most common causes of early death in people with spinal cord injury. Physical activity at high intensity is known to reduce the risk of cardiovascular disease in other patient groups. During aerobic training, combining functional electrical stimulation (FES) with voluntary arm-work induces a higher oxygen uptake than FES cycling alone and high intensity interval training induces higher oxygen uptake than training at continuous intensity. The hypothesis is that combining hybrid training with high-intensity induces even higher oxygen uptake thereby reducing the risk of cardiovascular disease. This training modality has not been tested before, so before conducting a randomized controlled trial testing the effect of this training modality on oxygen uptake, the aim was to asses safety and feasibility of this protocol.

Registry
clinicaltrials.gov
Start Date
January 30, 2018
End Date
June 1, 2018
Last Updated
6 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • spinal cord injury paraplegia,
  • complete and incomplete lesions,
  • ability to be electrically stimulated,
  • willing to train 3 times a week at high intensity

Exclusion Criteria

  • heart pacemaker or other heart problems contradicting high intensity aerobic training,
  • pregnancy,
  • unstable fractures,
  • heterotopic ossification,
  • myositis ossificans,
  • severe osteoporosis,
  • pressure ulcers,
  • newly implanted metal,
  • newly surgery,
  • frequent episodes of autonomic hyperreflexia,

Outcomes

Primary Outcomes

Number of serious adverse events

Time Frame: 8 weeks

Assessed by number of incidences of autonomic hyperreflexia or acute cardiac events

intensity

Time Frame: 8 weeks

Assessed as mean intensity of the 4 x 4 min. intervals as proportion of peak watt measured at baseline test. Peakwatt for FES-cycling was defined as an average of the three highest watt values within 30 sec. For skiergometer peak watt was defined as the highest average of one min. splits.

Shoulder pain

Time Frame: 8 weeks

Measured using Wheelchair Shoulder Pain Index (WUSPI), a 15 item questionnaire measuring shoulder pain during daily activities. Each item is scored on a 10 mm visual analog scale with anchors no pain to worst pain ever. Total index score range from 0 - 100. Within each item there is a not applicable option. The score used is performance corrected WUSPI score, dividing total index score by number of item responses and multiplied by 15. Higher score indicate higher level of shoulder pain.

compliance

Time Frame: 8 weeks

Assessed with number of dropouts and proportion of fulfilled training minutes

Secondary Outcomes

  • Peak oxygen uptake(8 weeks)
  • leisure time physical activity(8 weeks)
  • health related quality of life(8 weeks)
  • Fatigue(8 weeks)

Study Sites (1)

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