NL-OMON48731招募中不适用
MAGnesium In Chronic HemoDialysis; A clinical trial assessing the feasibility of increasing plasma magnesium concentrations by means of increasing dialysate magnesium concentrations in chronic hemodialysis patients. - MAGIC-HD
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 53
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Age 18 or above
- •- Hemodialysis with regular three times weekly dialysis schedule
- •- Hemodialysis since at least 3 months
- •- Standard dialysate Mg2+ concentration 0.50 mmol/L
- •- Providing informed consent
- •- Pre-dialysis plasma magnesium concentration 1.00 mmol/L or below
排除标准
- •- Intravenous magnesium supplementation (including total parenteral nutrition)
- •in the last 2 weeks
- •- Expected cessation of hemodialysis treatment within three months after
- •inclusion or expected permanent or temporary dialysis center switch to a center
- •not participating in the trial within three months after inclusion.
- •- Prolongation of QTc interval: male >450ms or female >460ms on baseline ECG
- •- Bradycardia: heart rate below 60 beats per minute on baseline ECG
- •- Chronic arrythmia or cardiac conduction disorder other than atrial
- •fibrillation or ventricular extrasystole that poses the patient at risk at the
- •discretion of the treating physician.
- •- Change of protonpumpinhibitor prescription in the last 2 weeks
研究者
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