Epidural anesthesia for OPCAB, a randomized comparison between general anesthesia alone or general anesthesia combined with high thoracic epidural anesthesia for off pump CABG

Completed

• Conditions: atherosclerosis; Hardening of the arteries; 10011082

• Registration Number: NL-OMON40349
• Lead Sponsor: Medisch Spectrum Twente

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 1400

Inclusion Criteria

-Men + Women 18 years or more
-Planned off pump CABG
-life expectancy at least 2 years
-fulfilled the criteria for the anticoagulation status to perform an epidural puncture

Exclusion Criteria

-no other off pump procedures planned (such as mini Maze)
-ongoing myocardial infarction or recent myocardial infarction in whom the cardiac enzymes have not returned to normal values
-necessitating intra aortic counter pulsation (left main stenosis)
-chronic renal failure, necessitating dialysis

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary endpoint of this study is the composite outcome of 30 days all<br /><br>cause mortality, myocardial infarction, stroke or renal failure requiring<br /><br>dialysis. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary endpoints are the separate components of the composite outcome.</p><br>