The Effects of Intraoperative Oxygen Used at Different Concentrations on Oxidatıve Stress Markers

Zonguldak Bulent Ecevit University1 site in 1 country40 target enrollmentFebruary 1, 2021

ConditionsStress Hyperoxia

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Stress
Sponsor: Zonguldak Bulent Ecevit University
Enrollment: 40
Locations: 1
Primary Endpoint: EFFECTS OF INTRAOPERATIVE OXYGEN USED AT DIFFERENT CONCENTRATIONS ON OXIDATIVE STRESS MARKERS
Status: Completed
Last Updated: 4 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The aim of the study was to assess the effect of intraoperative oxygen (O2), which was applied at 30% and 50% concentrations on patients who had undergone septoplasty surgery, on Total Oxidant Status (TOS), Total Antioxidant Status (TAS), and Oxidative Stress Index (OSI).

Registry

clinicaltrials.gov

Start Date

February 1, 2021

End Date

May 30, 2021

Last Updated

4 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Zonguldak Bulent Ecevit University

Responsible Party

Principal Investigator

Gamze Küçükosman

Principal investigator

Zonguldak Bulent Ecevit University

Eligibility Criteria

Inclusion Criteria

•patients aged between 18-60 years,
•ASA I-II risk class with a minimum operative time of 1.5 hour(s) for whom septoplasty operation under elective conditions

Exclusion Criteria

•metabolic, endocrine, hepatic, cardiac, or renal diseases,
•malignancies and who used a drug with antioxidant properties such as vitamin E-C
•acetylcysteine in the last 48 hours,
•patients requiring intraoperative 100% O2 inhalation