MedPath

Trial on Endovascular Management of Unruptured Aneurysms

Not Applicable
Conditions
Intracranial aneurysm
Circulatory System
Registration Number
ISRCTN62758344
Lead Sponsor
Centre Hosp. de l'Université de Montréal (CHUM) (Canada)
Brief Summary

2007 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/17316800 2008 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/22518212 2008 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/18631395

Detailed Description

Not available

Recruitment & Eligibility

Status
Stopped
Sex
All
Target Recruitment
2000
Inclusion Criteria

1. At least one documented subarachnoid aneurysm between 3 and 25 mm, never ruptured
2. Patient aged 18 or older, either sex
3. Life expectancy more than ten years

Exclusion Criteria

1. Patients with intracranial haemorrhage
2. Lesion characteristics unsuitable for endovascular treatment
3. Patients with single cavernous aneurysms
4. Aneurysms less than 3 mm or giant aneurysms (more than or equal to 25 mm)
5. Patients with a poor outcome (Rankin scale more than or equal to three) after the rupture, surgical or endovascular treatment of another aneurysm
6. Patients with incompletely treated aneurysms that have previously ruptured
7. Patients with associated arteriovenous malformations
8. Patients with new severe progressive symptoms in relationship with the aneurysm (sudden onset, severe persisting headaches suggestive of impending rupture, third-nerve palsy, mass-effect)
9. Patients with previous intracranial haemorrhage from unknown aetiology
10. Patients with multiple unruptured aneurysms in whom surgical clipping of one or many aneurysms is planned in addition to endovascular management
11. Patients with absolute contraindications to anaesthesia, endovascular treatment, or administration of contrast material, including low-osmolarity agents or gadolinium
12. Pregnant patients

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath