Oral hypoglycaemic activity of Pleurotus mushrooms on diabetic subjects
Not Applicable
Recruiting
- Conditions
- Diabetes mellitus
- Registration Number
- SLCTR/2013/021
- Lead Sponsor
- niversity of Sri Jayewardenepura
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
1.Type 2 diabetic patients
2.On diet control only
3.Ability to read and understand Sinhala and English
Exclusion Criteria
1.Type 1 diabetics
2.Pregnancy /breastfeeding
3.Patients on any oral hypoglycaemic medication
4.Patients on insulin
5.Patients on herbal medications known to have an effect on blood glucose
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fasting blood glucose<br> [Prior to administration of the mushroom suspension<br>]<br>Post glucose loaded (OGTT) blood glucose [2 hours after glucose load.]<br>Serum insulin levels (using ELIZA kits) [2 hours after glucose load.]<br>
- Secondary Outcome Measures
Name Time Method Change in liver function : serum alanine amino transferase, aspartate amino transferase, alkaline phosphatase, gamma glutamyl transpeptidase <br><br> [At base line and at the end of 4 weeks<br><br>]<br>Change in renal function : serum creatinine [At baseline and at the end of 4 weeks]<br>