Trendelenburg Maneuver Predicts Fluid Responsiveness in Patients With Extracorporeal Membrane Oxygenation (TEMPLE)
Not Applicable
- Conditions
- Extracorporeal Membrane Oxygenation
- Interventions
- Diagnostic Test: Trendelenburg Maneuver
- Registration Number
- NCT03553459
- Lead Sponsor
- Shanghai Zhongshan Hospital
- Brief Summary
The purpose of the study is to verify the efficacy of using trendelenburg maneuver to predict fluid responsiveness in patients with extracorporeal membrane oxygenation
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- patients with ECMO and mechanical ventilator support
- hypotension (MAP<65mmHg)
- required volume expansion by clinical judgement of the intensivists
Exclusion Criteria
- severe hypotension with high dose of vasopressors
- severe valve regurgitation
- cardiac arrhythmia
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Trendelenburg Maneuver Trendelenburg Maneuver Trendelenburg maneuver is performed to predict fluid responsiveness. Responders are defined by an increase in stroke volume over 15% after infusion of 500ml of crystalloid solution.
- Primary Outcome Measures
Name Time Method nonresponders within 1 minute after volume expansion nonresponders are defined by stroke volume increases less than 15% after volume expansion of 500ml crystalloid
responders within 1 minute after volume expansion responders are defined by stroke volume increases over 15% after volume expansion of 500ml crystalloid
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Zhongshan hospital, Fudan university
🇨🇳Shanghai, China