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Clinical Trials/NCT05886179
NCT05886179
Completed
Not Applicable

Factors Associated With COVID-19 in Children Aged 0-15 Years in Niger, 2020

Centre de Recherche Médicale et Sanitaire1 site in 1 country572 target enrollmentFebruary 25, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
to Contribute to a Better Control of COVID-19 in Children in Niger
Sponsor
Centre de Recherche Médicale et Sanitaire
Enrollment
572
Locations
1
Primary Endpoint
data base analysis
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

On January 30, 2020, the WHO declared COVID-19 a global health emergency. Children were affected with less severe forms. Niger had implemented measures in a context where children are a source of contamination. The objective was to determine the factors associated with COVID-19 in children in Niger from February to August 2020 through an analysis of the national database.

Detailed Description

We conducted an analytical cross-sectional study including all COVID-19 suspects in the database. We used Excel and Epi Info 7.2.4. software for data extraction and analysis. Frequencies and proportions were calculated, we estimated in a logistic regression the OR of association with their 95% confidence interval, the factors associated with COVID-19 at the threshold of p\<0.05. Results: Of 572 notified suspected COVID-19 cases in children aged 0-15 years, 11.36% were positive. The median age of infected children was 10 years \[IQR: 5- 13 years\]. The sex ratio of males to females was 2.1. Children aged 11-15 years were 49.2%, 61.5% resided in Niamey, 4.6% had comorbidities. The notion of travel was 12.3% and 40% had a notion of contact, 24.4% had a fever, 23.2% had a cough, 18% were hospitalized and the case fatality was 1.5%. In etiological analysis, the factors associated with COVID-19 were sex ORa= 0.51 \[0.28-0.93\] p=0.028, the presence of symptoms ORa= 2.29 \[1.23-4.25\] p=0.008 and the notion of contact ORa= 0.32 \[0.13-0.77\] p=0.011. exposed children were sensitive to COVID-19, all age groups were affected with a male predominance. We recommend barrier measures adapted to young people, early detection and management of infected children.

Registry
clinicaltrials.gov
Start Date
February 25, 2020
End Date
January 15, 2021
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Centre de Recherche Médicale et Sanitaire
Responsible Party
Principal Investigator
Principal Investigator

IDE AMADOU Habibatou

Doctor

Centre de Recherche Médicale et Sanitaire

Eligibility Criteria

Inclusion Criteria

  • Children aged 0-15 years suspected of having COVID-19 whose data were in the DSRE database were included

Exclusion Criteria

  • Children whose data is not complete

Outcomes

Primary Outcomes

data base analysis

Time Frame: May 2021

The first step concerned the descriptive part where the frequencies, proportions, means and extreme values of the variables were calculated. Some of these variables were presented in the form of tables and graphs.

Study Sites (1)

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