TO COMPARE THE EFFECTIVENESS OF TWO CHOLESTEROL LOWERING DRUGS IN PATIENTS WITH HIGH CHOLESTERO

Not Applicable

• Conditions: Health Condition 1: null- HYPERCHOLESTROLEMIC PATIENTS

• Registration Number: CTRI/2013/07/003842
• Lead Sponsor: FR MULLER MEDICAL COLLEGE

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

•Males and females (age 18-75 years).

•Non-pregnant, non-lactating female.

•Eligible and able to participate and have given informed consent.

•Diagnosis of hypercholesterolemia

Exclusion Criteria

•History of pancreatic injury or pancreatitis, or impaired pancreatic function/injury.

•Liver disease.

•Impaired renal function.

•Uncontrolled hypothyroidism.

•Severe acute illness or severe trauma in the last 3 months.

•Major surgery, 3 months prior to Visit 1.

•Significant cardiovascular disease (CVD) prior to randomization.

•Evidence of symptomatic heart failure, gross cardiac enlargement; significant heart block or cardiac arrhythmias.

•History of uncontrolled complex ventricular arrhythmias, uncontrolled atrial fibrillation/flutter or uncontrolled supraventricular tachycardias with a ventricular response rate of >100 beats per minute at rest.

•History of symptomatic cerebrovascular disease.

•Known muscular or neuromuscular disease of any type.

•Neoplastic disease.

•Current or recent use of supplements known to alter lipid metabolism.

•Hypersensitivity reactions to other HMG-CoA reductase inhibitors.

•Resistant to lipid-lowering medications, known hypersensitivity or intolerance to any lipid lowering agent.

•Signs of mental dysfunction or other factors likely to limit ability to cooperate.

Study & Design

• Study Type: Interventional
• Study Design: Not specified