The Objective Assessment and Characteristics of Dry Nose From Clinical Perspective

Completed

• Conditions: Diagnostic Self Evaluation
• Interventions: Diagnostic Test: test strips,sponges and cold dry air test

• Registration Number: NCT05401344
• Lead Sponsor: Beijing Tongren Hospital

Brief Summary

In the present study, we propose objective diagnostic criteria for dry nose (DN) and investigate its characteristics. Questionnaires were completed by each participant during recruitment to record demographic data. DN test strips were used to evaluate the severity of DN at five time points and allergic status was assessed based on serum sIgE levels. Nasal secretions were collected and vasomotor rhinitis was diagnosed using the cold dry air test. The diagnosis of allergic rhinitis (AR) was based on the criteria of the Allergic Rhinitis and its Impact on Asthma consensus statement. Data are expressed as median and interquartile range, unless otherwise specified. Statistical significance was set at P \< 0.05. The reference range (RR) of the 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentiles were determined for each test strip length at each time point. This study aimed to investigate the characteristics of and propose objective diagnostic criteria for DN.

Detailed Description

Not available

Study Timeline

• Status Verified: 2018-12
• Study Start: 2018-12-11
• Primary Completion: 2021-07-24
• Study Completion: 2021-10-31
• Study First Submitted: 2022-05-26
• Study First Submitted QC: 2022-05-29
• Last Update Submitted: 2022-05-29
• Study First Posted: 2022-06-02
• Last Update Posted: 2022-06-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• Clinical diagnosis of dry nose patients.

Exclusion Criteria

• chronic rhinosinusitis and/or nasal polyposis, allergic fungal rhinosinusitis, immunological disease, tumor patients, pregnant women.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
normal controls	test strips,sponges and cold dry air test	-
dry nose patients	test strips,sponges and cold dry air test	-

Primary Outcome Measures

Name	Time	Method
The length of the test strip.	5 minutes	We propose that the diagnostic criterion for DN is a strip length less than 17.0 mm at 5 min.

Trial Locations

Locations (1)

Yifan Meng; 🇨🇳 Beijing, Beijing, China