Does Muscle Wasting Always Mean Muscle Weakness? A Prevalence Study in COPD

Completed

• Conditions: COPD

• Registration Number: NCT02080936
• Lead Sponsor: 5 Santé

Brief Summary

Peripheral muscle mass and strength are relevant indicators of COPD survival. Current guidelines recommend to assess muscle strength only in muscle wasted patients. However, a recent study reported quadriceps weakness without muscle wasting (Menon, M et al. Resp. Res.2012, 13:119). Thus, these guidelines raise the risk to miss out some weak patients. In clinical settings, fat-free-mass index (FFMI) is indicated as a simple index to assess muscle wasting. We aimed at determining the prevalence of patients entering in pulmonary rehabilitation (PR) a priori not eligible for muscle strength evaluation given the lack of muscle wasting clinical signs.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-01
• Status Verified: 2014-03
• Primary Completion: 2014-03
• Study Completion: 2014-03
• Study First Submitted: 2014-03-05
• Study First Submitted QC: 2014-03-06
• Last Update Submitted: 2014-03-06
• Study First Posted: 2014-03-07
• Last Update Posted: 2014-03-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 138

Inclusion Criteria

• Patients who have got FFMI (bioimpedance)
• Patients who have done quadriceps muscle strenght evaluation

Exclusion Criteria

• Patients without FFMI
• Patients without quadriceps muscle strenght

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Muscle wasting in COPD patient	baseline

Secondary Outcome Measures

Name	Time	Method
Muscle weakness in COPD patient	baseline

Trial Locations

Locations (1)

Clinique du Souffle La Vallonie; 🇫🇷 Lodeve, France