Emotional Brain Processes in Recreational Cannabis Users

Completed

• Conditions: Recreational Cannabis Use
• Interventions: Other: fMRI

• Registration Number: NCT02801214
• Lead Sponsor: University of Electronic Science and Technology of China

Brief Summary

This fMRI study investigates neural correlates of emotion regulation, emotion processing and craving in recreational cannabis users.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-05
• Primary Completion: 2015-12
• Study First Submitted: 2016-06-11
• Study First Submitted QC: 2016-06-11
• Study First Posted: 2016-06-15
• Study Completion: 2016-12
• Status Verified: 2017-02
• Last Update Submitted: 2017-02-01
• Last Update Posted: 2017-02-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 50

Inclusion Criteria

• Recreational cannabis use
• 72 hours of abstinence

Exclusion Criteria

• neurological disorders
• psychiatric disorders according to DSM-4

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Healthy control subjects	fMRI	socio-demographically matched
Recreational Cannabis Use	fMRI	ages 18-40

Primary Outcome Measures

Name	Time	Method
fMRI neural correlates of emotional brain processes in recreational cannabis users after 72 hours of abstinence	one time point = fMRI assessment after 72 hours of abstinence	Activation patterns in brain regions known to be involved in emotional processing and to be altered by cannabis use (e.g. striatum, prefrontal cortex, insula, ACC)

Secondary Outcome Measures

Name	Time	Method
Ratings of subjective experience (affect, craving)	one time point = during fMRI assessment after 72 hours of abstinence