CTRI/2023/05/053069已完成不适用
SAFETY AND EFFICACY OF AUTOINOCULATION THERAPY IN CHRONIC RECALCITRANT DERMATOPHYTOSIS: A RANDOMIZED CONTROLLED TRAIL
SRMS IMS MEDICAL COLLEGE1 个研究点 分布在 1 个国家目标入组 52 人开始时间: 2023年5月6日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- AUTOINOCULATION FROM KOH POSITIVE SITE WILL BE PERFORMED
研究概览
简要总结
- Dermatophytosis is prevalent in about20%–25% of total world population.
- Dermatophytes includes group ofsuperficial filamentous fungi which infect the skin, nails and hair.
- There is a rising trend ofpatients experiencing extensive, recalcitrant and relapse of dermatophytosis.
- Antifungal agents usedconventionally are losing their relevance in the current clinical scenario.
- Homologous autoinoculation will be done after an interval of 21 days
- .
The 4mm tissue from koh positive site will be harvested and after breaking into small chunks, gently introduced deep into thesubcutis using 16-gaugeneedle.
- Homogolus autoinoculation offers safe and effective treatment modality for tackling dermatophytic epidemic.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients giving written informed consent.
- •Patients allowing to take photographs.
- •All patients of dermatophytosis showing positive result on KOH mount Patients of chronic recalcitrant1 dermatophytosis.
排除标准
- •Patients refusing to participate in the study.
- •Patients not willing to give written informed consent/click photographs.
- •Pregnant/lactating females.
- •Patients with concomitant chronic systemic disease like Hypertension, Diabetes mellitus or on immunosuppressant drugs.
- •Patients showing hypersensitivity to lignocaine.
结局指标
主要结局
AUTOINOCULATION FROM KOH POSITIVE SITE WILL BE PERFORMED
时间窗: BASELINE , 3 WEEKS , 6 WEEKS , 9 WEEKS
次要结局
- PATIENT SATISFACTION GRADE WILL BE TAKEN INTO ACCOUNT ON EACH VISIT.(BASELINE , 3 WEEKS , 6 WEEKS , 9 WEEKS)
研究者
研究点 (1)
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