autoinoculation therapy in dermatophytosis

Completed

• Conditions: Other specified local infections of the skin and subcutaneous tissue,

• Registration Number: CTRI/2023/05/053069
• Lead Sponsor: SRMS IMS MEDICAL COLLEGE

Brief Summary

- Dermatophytosis is prevalent in about20%–25% of total world population.

- Dermatophytes includes group ofsuperficial filamentous fungi which infect the skin, nails and hair.

- There is a rising trend ofpatients experiencing extensive, recalcitrant and relapse of dermatophytosis.

- Antifungal agents usedconventionally are losing their relevance in the current clinical scenario.

- Homologous   autoinoculation will be  done  after  an interval of 21 days

- .

The 4mm tissue from koh positive site will be harvested and after breaking into small chunks, gently introduced deep into thesubcutis using 16-gaugeneedle.

- Homogolus autoinoculation offers safe and effective treatment modality for tackling dermatophytic epidemic.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-05-06
• Study Completion: 2024-02-07
• Last Update Posted: 2024-03-07

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

• Patients giving written informed consent.
• Patients allowing to take photographs.
• All patients of dermatophytosis showing positive result on KOH mount Patients of chronic recalcitrant1 dermatophytosis.

Exclusion Criteria

• Patients refusing to participate in the study.
• Patients not willing to give written informed consent/click photographs.
• Pregnant/lactating females.
• Patients with concomitant chronic systemic disease like Hypertension, Diabetes mellitus or on immunosuppressant drugs.
• Patients showing hypersensitivity to lignocaine.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
AUTOINOCULATION FROM KOH POSITIVE SITE WILL BE PERFORMED	BASELINE , 3 WEEKS , 6 WEEKS , 9 WEEKS

Secondary Outcome Measures

Name	Time	Method
PATIENT SATISFACTION GRADE WILL BE TAKEN INTO ACCOUNT ON EACH VISIT.	BASELINE , 3 WEEKS , 6 WEEKS , 9 WEEKS

Trial Locations

Locations (1)

SRMS INSTITUTE OF MEDICAL SCIENCES; 🇮🇳 Bareilly, UTTAR PRADESH, India

SRMS INSTITUTE OF MEDICAL SCIENCES

🇮🇳Bareilly, UTTAR PRADESH, India

DR ARUJ DUDEA

Principal investigator

7906721172

aruj.srmsim@gmail.com