Cognitive rehabilitation in brain tumor patients after neurosurgery

Completed

Conditions: Cognitieve stoornissen
Cognitive deficits
memory and attention problems
10029211
10009720

Registration Number: NL-OMON44894

Lead Sponsor: Sint Elisabeth Ziekenhuis

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 150

Inclusion Criteria

* The patient has a brain tumor that is radiologically suspect for either a meningioma or low grade glioma.
* The patient will undergo craniotomy for the brain tumor.
* The patient is in clinical reasonable or good condition (Karnovsky performance Scale ><=70) .

Exclusion Criteria

Resection of the tumor in the last year, comorbid neurodegenerative disease, psychiatric or neurological disorder in the last 2 years, chemotherapy in the last 2 years, lack of basic proficiency in Dutch, IQ below 85, or (very) low cognitive skills, Karnovsky Performance Scale under 70, complete unfamiliarity with the use of computers, surgery-related complication (morbidity or mortality e.g., thrombosis or heart attack), and insufficient reading skills (limiting the ability to follow the cognitive rehabilitation program) and cognitive rehabilitation elsewhere.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Feasibility (adherence, patient experience, attrition) will be monitored in the<br /><br>feasibility study.<br /><br>Cognitive functioning: group and individual neuropsychological performance, as<br /><br>assessed with the computerized battery of neuropsychological tests and the two<br /><br>additional neuropsychological tests, at the 3 months, 6 months' and 12 months<br /><br>assessment as compared to baseline, and magnitude of change over time.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Self-reported symptoms/functioning: self-reported cognitive functioning,<br /><br>psychological symptoms (anxiety and depression), and fatigue as assessed with<br /><br>questionnaires at the 3, 6 and 12 months* assessment; professional functioning<br /><br>and community integration as assessed with questionnaires at the 12 months*<br /><br>assessment; self-reported and informant-reported executive functioning as<br /><br>assessed with a questionnaire at the 3 and 6 months' assessment. </p><br>