NCT02131831Unknown不适用
Telomeres Parameters in Cirrhosis
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- telomerase activity
研究概览
简要总结
There are several factors that influence telomere length in patients with cirrhosis, such as metabolic derangements and infectious etiologies, The aim of the study is to compare telomere length and other parameters related to genetic instability in telomere/ telomerase system, in peripheral blood lymphocytes in cirrhosis from different etiologies.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •cirrhotic patients from different etiologies
排除标准
- •decompensated cirrhosis (Child C)
- •age under 18 years
- •any known malignancy, including hepatocellular carcinoma
- •patient that are unable to sign for informed consent
结局指标
主要结局
telomerase activity
时间窗: baseline
number of copies of telomerase in peripheral blood lymphocytes, as determined by FISH
次要结局
未报告次要终点
研究者
ido laish
phsician in gastroenterology institute
Meir Medical Center
研究点 (1)
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