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Dose-intensified pirarubicin-cyclophosphamide, vincristine and prednisolone regimen (Double-THP-COP) followed by consolidative high-dose chemotherapy for peripheral T-cell lymphomas: a prospective phase II trial.

Phase 2
Conditions
ewly diagnosed adult peripheral T cell lymphoma patients, including those with peripheral T-cell lymphoma, not otherwise specified, angioimmunoblastic T-cell lymphoma, anaplastic large cell lymphoma (ALK negative), enteropathy-associated T-cell lymphoma, hepatosplenic T-cell lymphoma.
Registration Number
JPRN-UMIN000012664
Lead Sponsor
ihon University School of Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
25
Inclusion Criteria

Not provided

Exclusion Criteria

Eastern Cooperative Oncology Group (ECOG) performance status (PS) of 4 serum total Bilirubin > 1.5mg/dl serum creatinine >2.0mg/dl Ejection-Fraction<50% by electrocardiogram If these complications described above are considered to be attributed to underlying disease, those patients are included when the complications are recovered with the standard treatment. Invasion to the central nervous system from the first diagnosis

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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