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The role of procalcitonin in sepsis

Phase 2
Conditions
Condition 1: Sepsis. Condition 2: procalcitonin.
Sequelae of infectious and parasitic diseases
Abnormal findings on examination of blood, without diagnosis
B90-B94
R70-R79
Registration Number
IRCT201102065774N1
Lead Sponsor
vice-chancellor for research of Shahid Beheshti University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
150
Inclusion Criteria

All patients with clinical findings suggesting sepsis, All patients with clinical findings of systemic inflammatory response syndrome
Exclusion criteria:
All patients with clinical findings of systemic inflammatory response syndrome from non bacterial origin, viral or parasitic infections, patients who receive corticosteroids on immunosuppressive drugs, history of immunodeficiency, patient with central venous catheter and premature infant

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Procalcitonin. Timepoint: before and 6 hr and 24 hr after empiric antibiotic administration. Method of measurement: Immunoluminoassay ng/mL.
Secondary Outcome Measures
NameTimeMethod
Antibiogram. Timepoint: One time. Method of measurement: Resistantant, sensitive.;Empiric antibiotic. Timepoint: one time, after blood sampling withdrawn. Method of measurement: based on united state infectious disease guideline.;Time of clinical sign improved. Timepoint: Daily. Method of measurement: Clinical sign(fever).;Prognosis(death). Timepoint: Death. Method of measurement: Clinically.;Prognosis(life). Timepoint: Life. Method of measurement: Clinically.;Thyroid tumor. Timepoint: One time. Method of measurement: Clinical and laboratory investigation.;Immunosuppression. Timepoint: One time. Method of measurement: Clinical and laboratory investigation.
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