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临床试验/NCT01917786
NCT01917786已完成不适用

Effect of Dexmedetomidine on QT Interval in Pediatric Patients Under General Anesthesia

Senthil G. Krishna1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2013年7月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
50
试验地点
1
主要终点
Change in QT interval

研究概览

简要总结

Various medications used in anesthesia have been implicated in the prolongation of QT interval. Recently, there has been an increase in the use of dexmedetomidine in patients presenting for surgeries given its beneficial sedative, anxiolytic, and analgesic properties. It has several desirable properties including minimal respiratory side effects as well as the ability to decrease intraoperative and postoperative analgesic requirements. In many of the patients who present for routine surgical procedures, dexmedetomidine is a common component of their anesthetic care. This is a study to assess the effects of dexmedetomidine on the QT interval in children presenting for surgery.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

性别
All
接受健康志愿者
否

入选标准

  • •ASA grade 1 or
  • •Scheduled to receive dexmedetomidine.

排除标准

  • •Known allergy to dexmedetomidine.

结局指标

主要结局

Change in QT interval

时间窗: Baseline, 5 mins., 10 mins.

ECG will be done to assess QT interval prior to induction (baseline), after induction (5 mins.) and after dexmedetomidine (10 mins.)

次要结局

未报告次要终点

研究者

发起方
Senthil G. Krishna
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Senthil G. Krishna

Assistant Clinical Professor

Nationwide Children's Hospital

研究点 (1)

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