The Ketogenic Diet In Alzheimer's

Not Applicable

Completed

• Conditions: Alzheimer's disease; Neurological - Alzheimer's disease

• Registration Number: ACTRN12618001450202
• Lead Sponsor: Waikato Hospital Neurology Department

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-08-28
• Study Completion: 2020-05-08
• Last Update Posted: 26 July 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 26

Inclusion Criteria

(1) Aged 50 to 90 years.
(2) Satisfies revised NINCDS-ADRDA criteria for probable AD.
(3) Mild dementia (DSRS <19) and sufficient consent capacity (passing grade on a modified AD Informed Consent questionnaire, defined as at least 70% of questions 1 to 10 correct and 100% of questions 11 to 14 correct on the first or second administration, with the word medication” replaced with diet”).
(3) BMI >18.5.
(4) An active study partner able and willing to follow either diet plan.

Exclusion Criteria

(1)Inability to speak or understand English.
(2)Moderate or severe depression (short form Geriatric Depression score >8).
(3)Substantial concomitant cerebrovascular disease (Hachinski Ischemia score >4).
(4)Any change in dosage of an acetylcholinesterase inhibitor or memantine within 6 weeks before commencing the diets.
(5)A concurrent medical or psychiatric condition that in the opinion of the investigators would make it difficult to complete the study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified