TCTR20150607001
Completed
Phase 4
Attenuation of hemodynamic responses to laryngoscopy and intubation in hypertensive patients: Fentanyl versus Morphine plus Lidocaine
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Hypertensive patients who undergoing general anesthesia with tracheal intubation
- Sponsor
- Khon Kaen Hospital
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\.Age between 40\-65 years old
- •2\.Hypertensive patients (controlled BP \< 160/90 mmHg) ASA physical status II or III
- •3\.Elective surgery requiring general anesthesia with tracheal intubation
- •4\.Written informed consent obtained
Exclusion Criteria
- •1\.Cardiac surgery
- •2\.Pregnancy
- •3\.Obesity (body mass index \> 30\)
- •4\.Expected difficult intubation
- •5\.Nasogastric tube insertion
- •6\.Taking beta\-blockers
- •7\.Significant medical co\-morbidities (coronary artery disease, congestive heart failure, cardiac arrhythmia)
- •8\.Contraindication/precaution to lidocaine use (eg. evidence of heart block )
- •9\.Contraindication/precaution to morphine use (eg. asthma, COPD, chronic kidney disease stage 3 /GFR \< 60 ml/min/1\.73m2\)
- •10\.Allergy to study drugs
Outcomes
Primary Outcomes
Not specified
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