Prevalence and characteristics of Venous thromboembolism in patients of severe exacerbation of COPD

Not Applicable

Completed

• Conditions: Health Condition 1: J449- Chronic obstructive pulmonary disease, unspecified

• Registration Number: CTRI/2020/11/029073
• Lead Sponsor: AIIMS RISHIKESH

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 February 2023

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1.Consecutive patients admitted with the diagnosis of severe Acute Exacerbation of COPD.

2.Able to give informed consent.

3.Age between 40- 70 years

4. Severe AE-COPD will be defined as an event in the natural course of the disease characterised by a change in the patientâ??s baseline dyspnoea, cough, and/or sputum production that is beyond the normal day-to-day variations, acute in onset, and with sufficient severity warranting admission in the hospital.(GOLD guidelines 2018)

Exclusion Criteria

1.Admission because of reasons other than disease severity (distance, humanitarian concerns, etc.)

2.Not ready to give informed consent,

3.Pregnancy

4.Unfit to undergo CTPA because of impaired renal function or iodine allergy

5.Ongoing anticoagulant treatment for previous VTE or any other indication

6.Known hypercoagulable states like Protein C, S or AT deficiency or Factor V Leiden mutation.

Associated malignancy, left sided heart failure, or a debilitating neurological disease

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
prevalence of DVT or PE or both in AE-COPD.Timepoint: at baseline

Secondary Outcome Measures

Name	Time	Method
1.Radiological <br/ ><br>2.Clinical characteristics <br/ ><br>3.Echo characteristics <br/ ><br>4.short term outcomesTimepoint: short term outcomes-0,3,6 months <br/ ><br>Rest at baseline