A Clinical trial to study use of MRI DTI in identification of facial nerve in vestibular nerve schwannoma, a tumour of the nerve of hearing and balance
Phase 2
- Conditions
- Health Condition 1: null- PATIENTS WITH LARGE VESTIBULAR SCHWANNOMA MORE THAN 3 CM PLANNED FOR SURGERY
- Registration Number
- CTRI/2017/04/008345
- Lead Sponsor
- ALL INDIA INSTITUTE OF MEDICAL SCIENCES
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
Adult males or females with a diagnosis of vestibular schwannoma >3cm planned for surgery
- Who give consent to participate in study
Exclusion Criteria
-Patients in which there is computerized tomography evidence of calcification or hemorrhage as they are known to interfere with DTI tractography
-Those who do not consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Facial nerve preservation in intraop and immediate post-opTimepoint: Facial nerve preservation in intraop and immediate post-op
- Secondary Outcome Measures
Name Time Method FACIAL NERVE FUNCTION at 3 months follow upTimepoint: 3 months
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie facial nerve preservation using DTI tractography in vestibular schwannoma surgery?
How does preoperative MRI DTI tractography compare to standard imaging for facial nerve identification in large vestibular schwannomas?
Which biomarkers correlate with successful facial nerve function preservation in vestibular schwannoma patients using DTI?
What adverse events are associated with DTI-guided surgical approaches for large vestibular schwannomas and how are they managed?
Are there combination therapies or alternative imaging modalities that enhance outcomes compared to DTI tractography in vestibular schwannoma surgery?