Effectiveness of a Person-centred Prescription Model at the End of Life

Not Applicable

Completed

• Conditions: End-Of-Life; Deprescriptions; Inappropriate Prescribing; Palliative Medicine; Geriatrics

• Registration Number: NCT05454644
• Lead Sponsor: Matia Foundation

Brief Summary

This study's main objective is to investigate whether the application of an adapted person-centred prescription model during a hospital stay would reduce the use of inappropriate or futile regular medications in older people at the end of life, improving their clinical/health statuses and reducing the expense associated with pharmacological treatment. We hypothesised that applying this modified method could optimise pharmacotherapeutic indicators and the expense associated with the pharmacological treatment of hospitalised patients

Detailed Description

Not available

Study Timeline

• Study Start: 2018-02-15
• Primary Completion: 2020-02-28
• Study Completion: 2021-02-28
• Study First Submitted: 2022-06-30
• Status Verified: 2022-07
• Study First Submitted QC: 2022-07-07
• Last Update Submitted: 2022-07-07
• Study First Posted: 2022-07-12
• Last Update Posted: 2022-07-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 114

Inclusion Criteria

• Patients admitted to the geriatric convalescence unit and identified as having a non-oncological advanced chronic disease and being in need of palliative care, with a limited survival prognosis according to the necessity of palliative care (NECPAL) test.

Exclusion Criteria

• Patients with hospital stays of less than 72 hours.
• Patients transferred to other hospitals or units.
• Patients with imminently terminal patients.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change between admission and discharge in the number of regular medications.	3 months

Secondary Outcome Measures

Name	Time	Method
Change between admission and discharge in the STOPP Frail Criteria	3 months
Change between admission and discharge in the Drug Burden Index (DBI)	3 months
Change in the 28-day cost of prescriptions in €	3 months
Change between admission and discharge in the total drug-drug interactions	3 months
Change between admission and discharge in the Medication Regimen Complexity Index (MRCI)	3 months
Number of patients who have had unplanned hospital readmission	3 months
Number of patients who have had a new emergency department presentation.	3 months

Trial Locations

Locations (1)

Matia Foundation; 🇪🇸 Donostia, Gipuzkoa, Spain