Effect of Mobilization on Acute Postoperative Pain and Nociceptive Function

Completed

• Conditions: Pain, Postoperative; Pain Sensitivity, Postoperative

• Registration Number: NCT01018277
• Lead Sponsor: Hvidovre University Hospital

Brief Summary

Aim of the present study is twofold.

* First we want to evaluate the effect of mobilization on acute postoperative pain

* Second to test weather chances in pain sensitivity are occurring following surgery and mobilization after total knee arthroplasty

Detailed Description

Little is known about the effect of mobilization on acute postoperative pain and mobilization induced pain, and if altered pain sensitivity occur under these circumstances.

* First we want to evaluate the effect of mobilization on acute postoperative pain using the visual analog scale (VAS)

* Second to test weather chances in pain sensitivity are occurring following surgery and mobilization after total knee arthroplasty, using two simple tools, the Pain Matcher and a Pressure Algometer.

Study Timeline

• Study First Submitted: 2009-11-20
• Study First Submitted QC: 2009-11-20
• Study First Posted: 2009-11-23
• Study Start: 2009-12
• Primary Completion: 2010-06
• Study Completion: 2010-06
• Status Verified: 2012-04
• Last Update Submitted: 2012-04-19
• Last Update Posted: 2012-04-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 26

Inclusion Criteria

• Patients scheduled for total unilateral knee arthroplasty

Exclusion Criteria

• Cognitive dysfunction or peripheral / central neurological dysfunction inconsistent with protocol completing
• Alcohol and medical abuse (as defined by the National Health Service of Denmark
• Daily use of opioids or glucocorticoids

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain score on the visual analog scale (difference before and after two mobilisation seances)	up to 24 hours	pain at rest (supine) 5 min after exercise(after the 2nd walk)

Secondary Outcome Measures

Name	Time	Method
Pain score on the visual analog scale (difference before and after two mobilisation seances)	up to 24 hours	pain at rest (supine) 20 min after the 2nd walk, pain during passive hip flexion and pain during passive knee flexion 5 and 20 min after the 2nd walk, as well as pain during the 2nd walk after 6 and 25 m
Pain sensitivity measured with pressure algometry and with pain matcher (difference before and after two mobilisation seances and difference before and after surgery)	up to 24 hours	Nociceptive function before and after postoperative exercise

Trial Locations

Locations (1)

Hvidovre University Hospital; 🇩🇰 Copenhagen, Hvidovre, Denmark