临床试验/NCT03527901

NCT03527901已完成不适用

Evaluation of Active Matrix Metalloproteinase-8 (aMMP-8) Chair-side Test in Different Periodontal Disease and Healthy Implants

Aydin Adnan Menderes University0 个研究点目标入组 103 人开始时间: 2015年3月1日最近更新: 2018年5月17日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方
入组人数: 103
主要终点: aMMP-8 levels of GCF

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

The aim of this study to evaluate the diagnostic accuracy of a new qualitative aMMP-8 POC test in different periodontal health and disease and as compared to the established quantitative laboratory method (ELISA)

详细描述

MMP-8 has been reported to reflect the inflammatory status in periodontal tissues and, therefore represent as potential biomarkers of periodontitis. A positive aMMP-8 test could be an early indicator of these excessive and undesired tissue reactions.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Cross Sectional

入排标准

年龄范围: 20 Years 至 60 Years（Adult）
性别: All
接受健康志愿者: 否

入选标准

•Systemically healthy
•Nonsmokers

排除标准

•Participants were not included if they had systemic disease such as diabetes, cardiovascular.
•Participants who took regular medications that could affect of periodontal tissue
•Participants who received antibiotics less than 10 weeks before the study

结局指标

主要结局

aMMP-8 levels of GCF

时间窗: 2 hours

GCF levels measured by IFMA

次要结局

Salivary MMP-8 levels(2 hours)

研究者

发起方

Aydin Adnan Menderes University

申办方类型

Other

责任方

Principal Investigator

主要研究者

Veli Özgen Öztürk

Principal Investigator

Aydin Adnan Menderes University

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