Active Matrix Metalloproteinase-8 (aMMP-8) Chair-side Test in Different Periodontal Disease
- Conditions
- Periodontal Diseases
- Registration Number
- NCT03527901
- Lead Sponsor
- Aydin Adnan Menderes University
- Brief Summary
The aim of this study to evaluate the diagnostic accuracy of a new qualitative aMMP-8 POC test in different periodontal health and disease and as compared to the established quantitative laboratory method (ELISA)
- Detailed Description
MMP-8 has been reported to reflect the inflammatory status in periodontal tissues and, therefore represent as potential biomarkers of periodontitis. A positive aMMP-8 test could be an early indicator of these excessive and undesired tissue reactions.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 103
- Systemically healthy
- Nonsmokers
- Participants were not included if they had systemic disease such as diabetes, cardiovascular.
- Participants who took regular medications that could affect of periodontal tissue
- Participants who received antibiotics less than 10 weeks before the study
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method aMMP-8 levels of GCF 2 hours GCF levels measured by IFMA
- Secondary Outcome Measures
Name Time Method Salivary MMP-8 levels 2 hours Saliva levels measured by IFMA
Related Research Topics
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