Effect of Hyoscine and Promethazine on Labor Pain

Phase 2

Completed

• Conditions: Labor Pain
• Interventions: Drug: Promethazine; Drug: Hyoscine

• Registration Number: NCT01644838
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

It is always considered to shorten the duration of delivery without compromising the mother and fetus by obstetrics. Hyoscine and Promethazine are used widely in hospital and research is very limited, with conflicting results regarding the efficacy of these two drugs. So the investigators decided to compare of effect of hyoscine N-butyl bromide and Promethazine on length of active phase of the first stage of labor.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-08
• Primary Completion: 2011-03
• Study Completion: 2011-04
• Status Verified: 2012-07
• Study First Submitted: 2012-07-17
• Study First Submitted QC: 2012-07-18
• Study First Posted: 2012-07-19
• Last Update Submitted: 2012-07-19
• Last Update Posted: 2012-07-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 93

Inclusion Criteria

• 18-35 yrs,
• primiparous,
• having single fetus with cephalic presentation, gestational age 37-42 weeks,
• having no medical diseases,
• having no history of hospitalization due to psychological diseases,
• having no addiction to cigarette,
• having no complications during pregnancy such as hypertension,
• BMI< 26

Exclusion Criteria

• bleeding
• CPD
• use of PG or Oxytocin
• fetus distress

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Promethazine	Promethazine	25 mg of promethazine
Hyoscine	Hyoscine	20 mg of hyoscine

Primary Outcome Measures

Name	Time	Method
Effect of Hyoscine and Promethazine on labor pain	up to 9 months