Protein Consumption in Critically Ill Patients
Completed
- Conditions
- Dietary ModificationCritical Illness
- Registration Number
- NCT03048487
- Lead Sponsor
- Société des Produits Nestlé (SPN)
- Brief Summary
A retrospective study of protein intake and needs as well as outcomes in critically ill adult patients. Data will be collected for up to 7 days of ICU stay.
- Detailed Description
This retrospective study of critically ill adults receiving enteral nutrition will assess the ability to meet estimated protein and energy needs via enteral nutrition.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 2000
Inclusion Criteria
- Adult patients (age ≥18 years)
- Admitted to the ICU
- Administered at least one dose of enteral formula
Exclusion Criteria
- Receiving exclusive oral or exclusive parenteral nutrition
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Daily protein intake (from Parenteral Nutrition, Enteral Nutrition, oral diet, and medication) Daily up to 7 days of ICU stay
- Secondary Outcome Measures
Name Time Method Destination for discharge (home, another acute care hospital, Long Term Acute Care, rehabilitation center, nursing home) Through study completion, assessed an estimated 36 months Destination of Discharge will be assessed via chart review.
Neurocognitive status (Glasgow Coma Scale) Daily up to 7 days of ICU stay Presence of delirium (Yes/No) Daily up to 7 days of ICU stay ICU Length of Stay Up to 90 Days Ventilator days Up to 90 Days Death during hospitalization (Yes/No) Through study completion, assessed an estimated 36 months 30 day readmission Incidence up to 30 days post discharge Percentage of daily caloric needs met (%) calorie needs met. Daily up to 7 days of ICU stay Laboratory values (Alanine transaminase) Daily up to 7 days of ICU stay Gastrointestinal side effects observed in enterally fed patients in the ICU Daily up to 7 days of ICU stay Health Outcomes (Renal failure, Seizures, Encephalopathy, Hyperglycemia, Hypoglycemia) Daily up to 7 days of ICU stay Utilization of renal replacement therapy (Yes/No) Daily up to 7 days of ICU stay Laboratory values (Aspartate aminotransferase) Daily up to 7 days of ICU stay Daily caloric intake (from Parenteral Nutrition, Enteral Nutrition, oral diet, and medication) Daily up to 7 days of ICU stay Estimated caloric needs (Kcal/day) Daily up to 7 days of ICU stay Method for estimating protein needs (descriptive name of scale) Daily up to 7 days of ICU stay Utilization of medications to manage hepatic encephalopathy (lactulose) (Yes/No) Daily up to 7 days of ICU stay Antibiotic therapy days Up to 90 Days Enteral formula utilized (Standard, High protein, Very high protein) Daily up to 7 days of ICU stay Percentage of daily protein needs met (%) Daily up to 7 days of ICU stay Discharge against medical advice (Yes/No) Through study completion, assessed an estimated 36 months Method for estimating caloric needs (descriptive name of scale) calorie needs met. Daily up to 7 days of ICU stay Estimated protein needs (grams protein/day) Daily up to 7 days of ICU stay Laboratory values (Blood Urea Nitrogen) Daily up to 7 days of ICU stay Laboratory values (Creatinine) Daily up to 7 days of ICU stay Laboratory values (Glucose) Daily up to 7 days of ICU stay Laboratory values (Ammonia) Daily up to 7 days of ICU stay Insulin use Daily dose up to 7 days of ICU stay Hospital Length of Stay Up to 90 Days
Trial Locations
- Locations (3)
Geisinger Wyoming Valley Medical Center
🇺🇸Wilkes-Barre, Pennsylvania, United States
Geisinger Medical Center
🇺🇸Danville, Pennsylvania, United States
Geisinger Community Medical Center, Scranton, PA
🇺🇸Scranton, Pennsylvania, United States