NL-OMON36044已完成不适用
A randomized, double-blind, placebo-controlled first time into human study to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of intranasal dosing with GSK2245035, a TLR7 agonist, in healthy volunteers and allergic rhinitics - GSK2245035 SAD study in HV and rhinitis patients
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 75
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •healthy male volunteers
- •18 - 55 years of age
- •BMI 19 - 29.9 kg/m2;Part 2:
- •male volunteers with a pollen allergy
- •18 - 55 years of age
- •BMI 19 - 29.9 kg/m2
- •positive RAST test for pollen allergy
排除标准
- •- Suffering from: hepatitis B, cancer or HIV/AIDS
- •- Participation in another drug study within 3 months prior to dosing in this study
- •- Blood donation within 3 months prior to dosing in this study of donated more than 1.5 liters of blood in the 10 months prior to dosing in this study
研究者
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