Acute Neurocardiogenic Injury After Subarachnoid Hemorrhage Assessed With Cardiac 18F-FDG PET and 123I-MIBG Scintigraphy: a Prospective Observational Study.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- cardiac 18F-FDG PET
研究概览
简要总结
The aim of this study is to describe acute neurocardiogenic injury after subarachnoid hemorrhage assessed with cardiac 123I-MIBG scintigraphy and 18F-FDG PET/CT during the first week and the first six months after SAH.
The study hypothesis is that the evolution of the cardiac disturbances follows the clinical evolution.
详细描述
The cardiac metabolic disturbance are assessed by a 18F-FDG PET/CT in the first week after SAH and monthly until normal result.
The myocardial sympathetic innervation is assessed by a cardiac 123I-MIBG scintigraphy in the first week after SAH and six months later.
Clinical outcome is assessed by Glasgow Outcome Scale, modified Rankin Scale and MOS-SF36 at 1, 3 and 6 months after SAH.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hospitalization in the Military Teaching Hospital Sainte Anne
排除标准
- •Refusal of consent
结局指标
主要结局
cardiac 18F-FDG PET
时间窗: first week after SAH
次要结局
- cardiac 18F-FDG PET(one month after first cardiac 18F-FDG PET)
- cardiac 123I-MIBG scintigraphy(Six months after SAH)
研究者
PRUNET Bertrand
MD,MSc
Direction Centrale du Service de Santé des Armées