ISRCTN10399299已完成未知
Does cranberry extract reduce antibiotic use for symptoms of acute uncomplicated urinary tract infections? A feasibility study
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 81
研究概览
简要总结
2019 protocol in https://www.ncbi.nlm.nih.gov/pubmed/31870413 (added 31/12/2019) 2021 results in https://pubmed.ncbi.nlm.nih.gov/33619202/ (added 24/02/2021)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- Female
入选标准
- •1. Potential participant is willing and able to give informed consent for participation in the study
- •2. Female aged 18 years or above
- •CUTI Trial only:
- •1. Potential participant is making contact with general practice/primary care provider with urinary symptoms suggestive of acute, uncomplicated lower urinary tract infection (namely dysuria, urgency, frequency, polyuria/nocturia, haematuria and/or suprapubic pain), which the GP would normally treat with an immediate prescription of antibiotics
- •2. Symptom duration of under seven days (i.e. 6 days or less)
- •3. Potential participant is willing to receive either an immediate or delayed antibiotic prescription
- •CUTI Interviews only:
- •1. Has experienced one or more UTIs in the past 12 months
排除标准
- •CUTI Trial only:
- •The potential participant may not enter the study if ANY of the following apply:
- •1. Has taken antibiotics within the past 7 days
- •2. Cranberry allergy
- •3. Already taking cranberry products regularly
- •4. Known or suspected pregnancy
- •5. Breastfeeding
- •6. Warfarin user (cranberries may interact with Warfarin)
- •7. Unable to get a clean-catch/midstream urine sample
- •8. In-dwelling catheter
- •9. Receiving end of life care/palliative care
- •10. Known underlying structural urological abnormalities (including polycystic kidneys)
- •11. Previous urological surgery
- •12. Immunosuppressed [e.g. active cancer (excluding localised skin cancer), receiving chemotherapy, taking regular high dose oral steroids (> 5mg/day) , HIV infection]
- •13. Diabetes mellitus treated with insulin
- •14. Signs of clinically suspected upper UTI/pyelonephritis
- •15. Inability to complete symptom diary accurately (e.g. dementia or psychosis)
- •16. Is currently involved in an interventional research study on UTI
- •17. Unable to access internet/email over the next two weeks
- •18. Is unable to decide on the same day that they contacted a primary care provider whether they would like to participate
- •CUTI Interviews only:
- •1. Potential participant was immunosuppressed at the time of their UTI (including active cancer, receiving chemotherapy, diabetes mellitus treated with insulin or taking regular high-dose oral steroids (> 5 mg/day)
- •2. Potential participant has underlying urological abnormalities or has had previous urological surgery
- •3. Potential participant is receiving end of life care or palliative care
- •4. Potential participant declined to participate in the CUTI trial
研究者
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