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Clinical Trials/NCT01749449
NCT01749449CompletedNot Applicable

Increased Protein Intake and Meal Frequency Reduces Abdominal Fat and Increases Postprandial Thermogenesis During Energy Balance and Energy Deficit

Skidmore College1 site in 1 country30 target enrollmentStarted: January 1, 2005Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
30
Locations
1
Primary Endpoint
body composition

Study Overview

Brief Summary

The purpose of the current study was to examine the impact of macronutrient intake (PRO, 15% vs. 35%) and meal frequency (3 vs. 6 meals/day) on body composition, postprandial thermogenesis and plasma adipokines before and after 28days each of EB (28days) and ED (25%; 28days) in overweight individuals. We hypothesize that HP will elicit more favorable body composition, thermogenic, and cardiometabolic changes than HC intakes and the magnitude of change will be greatest in those consuming HP meals more frequently.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Prevention
Masking
None

Eligibility Criteria

Ages
30 Years to 65 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •30-65 years old,
  • •overweight or obese but otherwise in good health

Exclusion Criteria

  • •cardiovascular disease,
  • •type I or II DM,
  • •food allergies

Arms & Interventions

High protein 3 meals/day

Experimental

35% protein intake eaten as 3 meals per day

Intervention: protein and meal frequency (Other)

High carbohydrate consumed 3 meals/day

Experimental

High carbohydrate 3 meals/day

Intervention: protein and meal frequency (Other)

High protein consumed 6 meals/day

Experimental

35% protein 6 meals/day

Intervention: protein and meal frequency (Other)

Outcomes

Primary Outcomes

body composition

Time Frame: 2 months

DXA was used to quantify changes in body composition over the 2 months

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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