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Clinical Trials/NCT04539925
NCT04539925CompletedNot Applicable

Impact of Short-term Air Pollution Exposure on Acute Coronary Syndrome in Two Cohorts of Industrial and Non-industrial Areas: A Time Series Regression With 6,000,000 Person-years of Follow-up (ACS - Air Pollution Study)

Medical University of Silesia2 sites in 1 country9,046 target enrollmentStarted: December 1, 2019Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
9,046
Locations
2
Primary Endpoint
Non-ST segment elevation myocardial infarction

Study Overview

Brief Summary

Background: There is a lack of data on the effect of air pollution on acute coronary syndrome (ACS) in industrial and non-industrial areas.

Objectives: A comparison of association of air pollution exposure with ACS in two cohorts of industrially different areas.

Materials and methods: The study covered 6,000,000 person-years of follow-up and five types of air pollution between 2008 and 2017. A time series regression analysis with 7-lag was used to assess the effects air pollution on ACS.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Cross Sectional

Eligibility Criteria

Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Non-ST segment elevation myocardial infarction

Time Frame: 7 days

ST-segment elevation myocardial infarction

Time Frame: 7 days

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Wojciech Wańha

MD, PhD

Medical University of Silesia

Study Sites (2)

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