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Efficacy of Dual Focus Mutual Aid for Persons With Co-occurring Disorders

Not Applicable
Completed
Conditions
Substance Abuse
Mental Disorders
Interventions
Behavioral: Double Trouble in Recovery
Behavioral: Treatment as usual
Registration Number
NCT01333280
Lead Sponsor
Western Michigan University
Brief Summary

The purpose of the study is to determine whether adding "dual focus" mutual aid groups to formal treatment for people dually diagnosed with substance abuse and mental illness is effective in improving treatment outcomes.

NO VOLUNTEERS ARE ACCEPTED. ENROLLMENT IS LIMITED TO CLIENTS OF THE PARTICIPATING TREATMENT PROGRAMS.

Detailed Description

This study builds on two previous studies by the principal investigator, which found that participation in an established and growing "dual-focus" mutual aid model (Double Trouble in Recovery; DTR) by persons with co-occurring substance use and psychiatric disorders was associated with drug/alcohol abstinence and improved psychiatric outcomes. However, these findings are limited as they are based on studies using an observational design with existing DTR groups and a pre-post design with a historical control. This new application seeks to confirm and significantly extend this research by conducting a randomized clinical trial (RCT) of DTR at multiple treatment sites.

The specific study aims are:

1. To conduct a multi-site RCT to determine the efficacy of "dual focus" 12-step mutual aid groups for persons with co-occurring substance use and mental disorders. Substance-using patients who are admitted to psychiatric outpatient clinics will be randomly assigned within each clinic to (i) DTR group participation plus standard treatment, or (ii) standard treatment as usual (wait list for DTR). The primary outcome is drug/alcohol use. The secondary outcomes are psychiatric medication adherence; quality of life; treatment retention; and traditional 12 step group participation. Major assessments will occur at baseline and 6 months later.

2. To determine the therapeutic mechanisms mediating between DTR participation and behavioral outcomes. Hypothesized mediating variables will include both "common process" factors across treatments, e.g., coping, self-efficacy and social support; and factors relatively unique to mutual aid, e.g., mutual aid group processes, 12-step attitudes and spirituality.

3. To determine the personal, social/environmental and treatment-related variables which predict DTR affiliation.

4. To describe the development of DTR groups and the conditions needed to sustain them.

Federal substance abuse and mental health policy encourages the use of evidence-based interventions, yet rigorous evaluation data are scant for mutual aid groups. In particular, this research will lead to recommendations for improving the integration of formal treatment with mutual aid for persons with co-occurring disorders. Moreover, by conducting the proposed RCT, the study will substantially raise the standard by which mutual aid is evaluated.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
352
Inclusion Criteria
  • admission to one of the participating treatment programs
  • substance abuse/dependence
  • 18-65 years of age

NO VOLUNTEERS ARE ACCEPTED. ENROLLMENT IS LIMITED TO CLIENTS OF THE THE PARTICIPATING TREATMENT PROGRAMS.

Exclusion Criteria
  • Inability to conduct an interview in English or participate in English- language DTR groups
  • Appears intoxicated on drugs or alcohol
  • Carries a diagnosis of mental retardation
  • Deemed actively psychotic by the clinic's intake coordinator
  • Appears unable to understand and give informed consent.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Double Trouble (DTR) groupDouble Trouble in RecoveryDouble Trouble in Recovery groups
Treatment as usualTreatment as usualTreatment as usual while on a waiting list for DTR groups
Primary Outcome Measures
NameTimeMethod
Substance abuseStudy intake and six month follow-up

Self-reported substance use and saliva toxicology for drugs

Secondary Outcome Measures
NameTimeMethod
psychiatric medication adherencesix month follow-up

Self-reported adherence to prescribed medications

Traditional 12-step meeting participationsix month follow-up
Treatment retentionsix month follow-up
Quality of lifesix month follow-up

Trial Locations

Locations (4)

BRC

🇺🇸

New York, New York, United States

South Beach Psychiatric Center

🇺🇸

New York, New York, United States

Coney Island Hospital

🇺🇸

Brooklyn, New York, United States

Proaction Health Alliance

🇺🇸

Grand Rapids, Michigan, United States

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