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Evaluation of relationships between swallowing function and prognostic factors in patients with chronic obstructive pulmonary disease

Not Applicable
Conditions
Chronic Obstructive Pulmonary Disease
Registration Number
JPRN-UMIN000013861
Lead Sponsor
Kyoto University Hospital Clinical Research Center for Medical Equipment Development
Brief Summary

Breathing-swallowing discoordination is strongly associated with frequent exacerbations of COPD. Strategies that identify and improve breathing-swallowing coordination may be a new therapeutic treatment for patients with COPD.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
65
Inclusion Criteria

Not provided

Exclusion Criteria

1. Patients whose primary symptom is associated with bronchial asthma 2. Patients with malignant neoplasms or having histories of malignant diseases within 5 years 3. Patients with cerebrovascular diseases or having histories of cerebrovascular diseases 4. Patients having histories of aspiration pneumonia within 2 years 5. Patients taking dopaminergic drugs or ACE inhibitors 6. Patients treated with cardiac pacemakers 7. Patients with apparent dementia (MMSE < 20) 8. Patients who have difficulties in conducting spirometry 9. Patients who declined to participate in the study 10. Patients who were judged as inappropriate to be enrolled by the doctor in charge

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Exacerbation, decline of lung function, and progression of emphysema based on CT images within one year categorized by swallowing function at the start point
Secondary Outcome Measures
NameTimeMethod
Relationship between COPD staging and swallowing function
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