NCT00620178已完成不适用
A REtrospective Study on the Effects of cAndesartan vs. Losartan on Blood Pressure, Health Care Consumption and cardiovascuLar Events In a "Real-liFe" GP sEtting in Sweden
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- AstraZeneca
- 入组人数
- 14,000
- 试验地点
- 1
- 主要终点
- The primary efficacy objective is to investigate, on basis of 'first to event', the development of new cardiovascular diseases (CVD).
研究概览
简要总结
This study is a Swedish historical cohort study in patients prescribed Atacand or Cozaar for hypertension by selected primary care centres. Data will be extracted anonymously from electronic medical records. In addition, data regarding morbidity and mortality will be collected by merging the cohort with the following national registries: the Hospital Discharge Register (Slutenvårdsregistret), the Cause of Death Register and the Heart Intensive Care Admission (RIKS-HIA)
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 17 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Recorded blood pressure prior to therapy of > 140 and/or 90 mmHg
- •Diagnosed as hypertensive within 15 months
- •First prescription of Cozaar or Atacand between 1 January 1999 and 31 December 2007, inclusive
排除标准
- •Previous prescription within 15 months any drug from the ATC groups C02, C03, C07 - C09 inclusive
研究组 & 干预措施
1
Candesartan
干预措施: Candesartan Cilexetil (Drug)
2
Losartan
干预措施: Losartan (Drug)
结局指标
主要结局
The primary efficacy objective is to investigate, on basis of 'first to event', the development of new cardiovascular diseases (CVD).
时间窗: 1999 - 2007
次要结局
- Cardiovascular disease states and procedures in the background and over the entire observation period will be identified by use of ICD-9 and ICD-10 coding for diseases of the cardiovascular system. Specifically are death, acute cardiovascular events, new(1999 - 2007)
- Health care consumption will be assessed as contacts with health care providers, in-hospital time periods for cardiovascular disease states with associated therapeutic procedures, and times spent within various levels of care (e.g. ICU and general ward).(1999 - 2007)
研究者
研究点 (1)
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