NCT01374737UnknownPhase 4
ED50 of Dexmedetomidine for Reduction of Emergence Agitation Incidence Undergoing Tonsillectomy or Adenoidectomy in Desflurane Anesthesia Following Sevoflurane Induction in Children
Seoul National University Hospital1 site in 1 country25 target enrollmentStarted: June 2011Last updated:
Conditions
Interventions
Drugs
Trial Snapshot
- Phase
- Phase 4
- Enrollment
- 25
- Locations
- 1
- Primary Endpoint
- agitation
Study Overview
Brief Summary
There are several recommended doses of dexmedetomidine for prevention of emergence agitation in children. In this study, the investigators examine ED50 in prevention of emergence agitation after tonsillectomy or adenoidectomy in children.
Detailed Description
To investigate ED50, Dixon's up and down method will be used.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Single Group
- Primary Purpose
- Prevention
- Masking
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 2 Years to 12 Years (Child)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •tonsillectomy or adenoidectomy
Exclusion Criteria
- •recent URI
Arms & Interventions
dexmedetomidine, children
Other
Intervention: Dexmedetomidine (Drug)
Outcomes
Primary Outcomes
agitation
Time Frame: 30 minutes
Secondary Outcomes
- pain(30 minutes)
Investigators
Study Sites (1)
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