The effect of Naltrexone on memory deficit induced by Electroconvulsive therapy
Phase 2
- Conditions
- Condition 1: Depressive Episode. Condition 2: Memory deficit induced by electroconvulsive therapy.Depressive episode
- Registration Number
- IRCT2016060628309N1
- Lead Sponsor
- Vice chancellor for research,Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Inclusion criteria : aged 18 to 65 years; major depression or bipolar depression disorder patients based on DSM4 criteria; indicated for ECT
Exclusion criteria: affected by a prominent medical condition; diagnosed with schizophrenia or mania; a history of ECT in the last 6 month; recent opioid use
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Memory deficit. Timepoint: At the day before ECT sessions, two weeks, one month and three months after ECT sessions. Method of measurement: Wechsler memory test.
- Secondary Outcome Measures
Name Time Method Depression severity. Timepoint: Before and 3 months after ECT session. Method of measurement: Hamilton Depression Questionair.