Preemptive Analgesia With Morphine Sulphate in Major Urological Surgery

• Conditions: Pain

• Registration Number: NCT02041988
• Lead Sponsor: University of Roma La Sapienza

Brief Summary

In this study safety and efficacy of oral morphine sulphate is evaluated in order to reduce opioids administration during major urological surgery

Detailed Description

The administration of oral morphine sulfate could be useful to reduce the use of opioids in major urological surgery. This study aims to assess the safety and efficacy of two different oral morphine sulphate doses 0,2 mg/kg vs 0,4mg/kg in major urological surgery.

Study Timeline

• Study Start: 2013-02
• Study First Submitted: 2013-07-01
• Status Verified: 2014-01
• Primary Completion: 2014-01
• Study First Submitted QC: 2014-01-17
• Last Update Submitted: 2014-01-17
• Study First Posted: 2014-01-22
• Last Update Posted: 2014-01-22
• Study Completion: 2014-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

American Society of Anaesthesiologists physical status classification I/ II, age between 18 - 75, BMI 18 -30

Exclusion Criteria

American Society of Anaesthesiologists physical status classification III/ IV, renal and hepatic insufficiency, postoperative nausea and vomiting after oral opioids administrations, neurological and psychiatric disorders.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
morphine sulphate consumption	six months

Secondary Outcome Measures

Name	Time	Method
vital signs	six months

Trial Locations

Locations (2)

Policlinico Umberto I; 🇮🇹 Rome, Italy

Francesco Cannata; 🇮🇹 Rome, Italy