Clinical study of CCTA-FFRCT combined evaluation of coronary ischemia in early stage of coronary heart disease with traditional Chinese medicine

Phase 1

• Conditions: Stable Angina Pectoris of Coronary Heart Disease

• Registration Number: ITMCTR2022000025
• Lead Sponsor: Guang 'anmen Hospital, Chinese Academy of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

(1) It meets the diagnostic criteria of stable angina pectoris of coronary heart disease in Western medicine, and CTA shows that at least one major branch has a lumen diameter narrowing of 50%-75%; (2) 0.7 < FFRCT=0.8; (3) Meet the standard of TCM syndrome differentiation of chest obstruction and blood stasis; (4) Aged 18-85, with no gender limitation; (5) those who have not taken other Chinese herbs in the last two weeks; (6) Those who voluntarily participate and sign the informed consent of patients.

Exclusion Criteria

(1) Patients with a history of acute myocardial infarction in the last 3 months; (2) Patients with a history of serious arrhythmias, such as ventricular fibrillation, degree III ATrioventricular block, etc.; (3) Poor blood pressure control (systolic blood pressure =180mmHg or diastolic blood pressure =120mmHg); (4) serious diseases of liver, kidney, respiratory system, blood system, endocrine system and malignant tumors; (5) Women who are currently preparing for pregnancy, pregnancy or breastfeeding; (6) severe cardiac neurosis, perimenopausal syndrome, etc.; (7) patients suffering from mental disorders, or serious alcoholism and other adverse intoxication; (8) allergic to Chinese herbal medicine; (9) Incomplete medical records; (10) The researchers assessed other conditions for exclusion. Those who meet any of the above criteria will not be included in the test.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
oninvasive Fractional Flow Reserve Derived from Coronary CT;

Secondary Outcome Measures

Name	Time	Method
TCM syndrome integral;Ultrasonic diastolic function parameter -- E/ e';