Use of Chewing Gum to Facilitate Appetite Control and Weight Loss

Not Applicable

Completed

• Conditions: Overweight; Obesity
• Interventions: Behavioral: Lifestyle modification; Behavioral: Lifestyle modification plus gum

• Registration Number: NCT00871676
• Lead Sponsor: University of Pennsylvania

Brief Summary

This purpose of this study was to test the use of chewing gum as an adjunct to lifestyle modification to facilitate appetite control and weight loss in overweight and obese individuals.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-05
• Status Verified: 2009-03
• Study First Submitted: 2009-03-27
• Study First Submitted QC: 2009-03-27
• Study First Posted: 2009-03-30
• Primary Completion: 2009-12
• Study Completion: 2009-12
• Last Update Submitted: 2016-08-15
• Last Update Posted: 2016-08-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 146

Inclusion Criteria

• 21-75 years of age
• Body Mass Index of 25-45 inclusive

Exclusion Criteria

• major medical psychiatric conditions
• medications know to effect weight
• full or partial dentures
• 18 or fewer teeth
• regular gum chewing (≥ 2 pieces/day)
• use of any tobacco product
• sensitivity to the following ingredients (mint, magnolia bark, eggs, or English Muffins)
• history of PKU
• sensitivity or allergy to aspartame
• current/history of alcohol abuse or addiction (within 5 year)
• recreational drug use
• recent significant weight change (+/- 5% in previous 6 months)
• currently pregnant or nursing and willingness not to get pregnant during course of study
• participation in any other research studies
• proximity to clinic (within one hour)
• access to reliable transportation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	Lifestyle modification	Overweight/obese individuals being treated with lifestyle modification to facilitate weight loss.
2	Lifestyle modification plus gum	Lifestyle modification plus use of chewing gum to facilitate weight loss in overweight/obese persons.

Primary Outcome Measures

Name	Time	Method
Weight loss	Week 16 and 52

Secondary Outcome Measures

Name	Time	Method
Appetite control	Weeks 4, 8, 12, 16 and 52

Trial Locations

Locations (1)

University of Pennsylvania School of Medicine; 🇺🇸 Philadelphia, Pennsylvania, United States