Physiological and Clinical Changes in NHF Therapy

Not Applicable

Completed

• Conditions: Interstitital Lung Disease; Hypercapnia; Chronic Obstructive Pulmonary Disease
• Interventions: Device: Nasal Highflow (NHF)

• Registration Number: NCT02504814
• Lead Sponsor: University of Leipzig

Brief Summary

The study explores the changes in pressure, volume and in hypercapnia in patients with COPD and ILD. The investigators will use different application forms.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-06
• Study First Submitted: 2015-05-27
• Study First Submitted QC: 2015-07-20
• Study First Posted: 2015-07-22
• Primary Completion: 2018-06
• Study Completion: 2018-06
• Status Verified: 2019-02
• Last Update Submitted: 2019-02-14
• Last Update Posted: 2019-02-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

• COPD, ILD

Exclusion Criteria

• Unstable disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
ventilatory effects	Nasal Highflow (NHF)	measuring mean airway pressure, breathing volumes and decrease in hypercapnia

Primary Outcome Measures

Name	Time	Method
changes in mean airway pressure (mbar)	1 month
changes in tidal and minute volume (l)	1 month
changes in breathing frequency (beats/ minute)	1 month

Secondary Outcome Measures

Name	Time	Method
changes in partial pressure of carbon dioxide (CO2) in arterial blood (pCO2)	4 month

Trial Locations

Locations (1)

Jens Bräunlich; 🇩🇪 Leipzig, Sachsen, Germany