Effect of Nasal Highflow on Right Heart Function

Not Applicable

Completed

• Conditions: Pulmonary Hypertension
• Interventions: Device: Nasal high flow (NHF) supplementation; Device: oxygen supplementation

• Registration Number: NCT02885116
• Lead Sponsor: University of Leipzig

Brief Summary

In this study effect of NHF on pulmonary thermodynamic parameters will studied.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-01
• Study First Submitted: 2016-08-22
• Study First Submitted QC: 2016-08-25
• Study First Posted: 2016-08-31
• Primary Completion: 2018-02
• Study Completion: 2018-02
• Status Verified: 2018-06
• Last Update Submitted: 2018-06-21
• Last Update Posted: 2018-06-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• stable disease
• hypoxemic respiratory disorder

Exclusion Criteria

• decompensation
• acute illness

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Nasal high flow (NHF) supplementation	Nasal high flow (NHF) supplementation	right heart catheterization after during NHF (20 min) use with 35 l/min
oxygen supplementation	oxygen supplementation	right heart catheterization will be done in hypoxemic patients with supplemental oxygen

Primary Outcome Measures

Name	Time	Method
changes in mean pulmonary pressure (PAPm)	20 min	measured in mmHg

Secondary Outcome Measures

Name	Time	Method
changes in cardiac index (CI)	20 min	l/min/qm
changes in wedge pressure (PC)	20 min	mmHg

Trial Locations

Locations (1)

Department of Respiratory Medicine; 🇩🇪 Leipzig, Sachsen, Germany