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Voorspellende waarde van soluble mesothelin-related peptide, CEA, Cyfra 21-1 and CA 125 bij patiënten met pleuravocht.

Not yet recruiting
Conditions
pleural effusion, tumour markers, mesothelin. pleuravocht, tumormarkers, mesotheline
Registration Number
NL-OMON20116
Lead Sponsor
Maatschap longziekten MST EnschedeMaatschap longziekten ZGT Almelo
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
120
Inclusion Criteria

1. Pleural fluid;

2. Age over 18 years;

Exclusion Criteria

1. Known cause of the pleural fluid;

2. Clinical and/or radiological suspicion for pleural empyema;

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To test the diagnostic capacity for malignancy in pleural fluid of the tumour markers SMRP, CEA, Cyfra 21-1 and Ca 125 by patients presenting with pleural fluid without any known or suspected cause.
Secondary Outcome Measures
NameTimeMethod
The prognostic capacity of the same markers in malignant pleural disease.
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